To diabetes there are associated various consequences, mainly connected to hyperglycemia, which may cause a diminished resistance to infections, an altered response of the host and changes of the periodontal tissue destructions. Early studies focused on PMN dysfunctions connected to diabetes, in a relationship with the periodontal disease. Later, at humans, the PMN defects were linked both on the periodontal disease and diabetes, since the chemotactic response of the PMN was mostly compromised at the diabetic patients with periodontal disease comparing with the
diabetic patients with a mild periodontal disease, or with the healthy patients with a mild or severe periodontal disease
(Manouchehr 1981, Bissada 1982).
- METABOLIC CONTROL
- PERIODONTAL DISEASE