At the level of the superficial periodontium, the free gingival mucosa can be repaired through regeneration, but the dento-gingival junction only supports cicatrisation. The aims of the study were: 1) documentation of the theoretical elements referring to the healing process of the wounds, especially from the level of the superficial periodontium, 2) clinico-morphological exam of the selected cases, 3) comparative evaluation of these cases, under the rapport of clinical and anatomo-pathological exam. Material and methods: We have studied on a group of 5 patients the possibilities of healing, repairing and regeneration of the superficial periodontal tissues, through anatomo-pathological exam of the fragments taken from the level of affected gingival mucosa. Each fragment of biopsy was initially fixed in phormole, than prepared according to the standard protocol for the anatomopathological exam.