Authors: Ioana Rudnic, Erika Rudnic, Silvia Mârtu


Aims This clinic and statistic study had as a purpose the evaluation of oral manifestations caused by infectious mononucleosis in correlation with systemic symptoms, lab results and general demographic features. Matherial and Method We choose for the study group 95 patients with infectious mononucleosis from Clinical Hospital of Infectious Diseases of Iasi during January 2005 –
December 2007. From the total number of 95 patients of our study group, 49 were mail and 46 were female. Results and discutions From the entire study group with infectious mononucleosis, 43 patients (45, 3%) did not present lesions of the oral mucosal membrane as a clinical symptom of this disease. The rest of 52 cases (54, 7%) presented oral manifestations determined by infectious mononucleosis. Oral symptoms of the patients infected with Epstein-Barr virus presented various forms of manifestatios.Most of the cases (19 cases – 20 % of total number of the study group) presented at clinical intraoral exam a hemorrhagic patch, a feature characteristic to this desease accordingy to literature data. A number of 15 cases (15, 8%) presented a diffuse erythema on oral mucosal membrane, which represents a clinical manifestation cited in the literature as being associated with infectious mononucleosis. Interesting is the fact that we noticed at a
relative increased number of cases ( 9 cases – 9,5% of total number of study group) multiple manifestations at oral mucousal membrane level; from these manifestation the most important was ulcero-necrotic gingivo-stomatitis, which can be associated with the imunocompromised host because of the prelonged period of evolution of the infectious mononucleosis. Conclusions Gate entrance of
the virus being into oral cavity, as well as the most of the clinical manifestations, is the dentist duty to identify the Epstein-Barr viral infection and to prevent its spreading into the population. If the dentist has a patient with an Epstein-Barr virus infection, he/she needs to postpone the dental treatment and to send the patient to Infectious Disease Clinic.