Pleomorphic adenoma, also known as benign mixed tumor, is the most common benign tumor of salivary glands that mostly occurs in the parotid or submandibular glands, but may also be found in the minor salivary glands that are distributed throughout the oral cavity. Surgical removal with adequate margins is the principal treatment. Due to its microscopic projections, this tumor requires a wide resection to avoid recurrence. We report a case of a pleomorphic adenoma in the upper lip, the second site for frequency for benign tumors of minor salivary glands, after the hard and soft palate.