CLINICAL RESEARCHES ON THE ADMINISTRATION OF AMOXYCYLIN AND METRONIDAZOLE AS AN ADJUVANT TREATMENT IN GENERALIZED AGGRESSIVE PERIODONTITES

Authors: Vanda Raluca Popa, Sorina Solomon, Ioana Rudnic, Silvia MÂRŢU

Abstract:

Scope of the study: The scope of the study was to demonstrate that the additional systemic medication 7 day cure with Metronidazole and Amoxycylin significantly modified the results of non-surgical treatment in patients suffering from generalized aggressive periodontitis (PAG).
Materials and method: The experimental group included 41 patients sufferring from PAG, with at least 3 sites at different teeth, and probing depth of the periodontal pockets (PPD) of 5-7 mm. The patients, divided into 2 groups, received identical recipients, containing either antibiotics or placebo. To the former group, first an antibiotic and then a placebo had been administered, while the latter received first placebo and then antibiotics.
Results: The main result of the measurements performed in the study, quite significant in the former group, was a reduction of PPD in the sites with an initial PPD =7mm.
Conclusions: The protocol of the present study permits the following conclusion: patients receiving antibiotics as an initial therapy evidenced significant improvements, comparatively with those who were given such treatments after the etiological one.

Keywords:
  • AGGRESSIVE PERIODONTITIS
  • antibiotherapy
  • antiinflammatory treatment