IMMUNO-BIOCHEMICAL AND CLINICAL RESEARCHES ON THE EVOLUTION OF ANTIOXIDANTS LEVEL IN THE ETIOPATHOGENY OF PERIODONTAL PATHOLOGIES

Authors: Oana Potârnichie, Sonia Nanescu, Liliana Pasarin, Ioana Rudnic, Liliana Foia, Silvia MÂRŢU

Abstract:

Introduction: A comprehensive, recent analysis on the topic reached the conclusion that oxidative stress is the main cause provoking destruction of the periodontal tissue resulting from the host-microbe interaction.
Scope of the study: To investigate the correlation between periodontal health condition and the seric levels of some antioxidants.
Materials and method: A representative group of 58 patients, with ages between 30 and 70 years, were examined, between 2010-2011, as to their periodontal condition, after which peripheric blood was taken over and retinol, -tocopherol, -tocopherol, caroten, caroten, -criptoxantine, zeaxantine, luteine and licopen were extracted from the serum. The values of the antioxidants were measured by high-performance chromatographic liquid technique.
Results: The levels of and caroten, -criptoxantine and zeaxantine were significantly lower in the patients with minimum periodonthopaty debut (p<0.001), as well as in those with increased intensity of periodontopathy debut. -caroten and -criptoxantine were the only antioxidants associated with a higher risk of severe periodontic pathologies. Conclusions: The low levels registered for some carotinoides, especially -caroten and -criptoxantine, are directly proportional with a higher prevalence of periodonthy installation.

Keywords:
  • antioxidants
  • oxidative stress
  • PERIODONTAL RISK