GINGIVAL HYPERPLASIA AND THE ANTIPHOSPHOLIPID SYNDROME WITH AUTOIMMUNE THROMBOCYTOPENIA – A CASE STUDY

Authors: M.C. Giurgiu, H.T. Dumitriu

Abstract:

The periodontal disease is a microbial inflammatory pathology, to which local and/systemic favourizing factors are associated, leading finally to teeth losses.
Scope. To establish an antibiotic treatment against a particular type of gingival hyperplasia, favourized by an antiphospholipid syndrome with thrombocytopenia.
Materials and method. Following the realization of the antibiogramme, a systemic antibiotic treatment was given to a patient with gingival hyperplasia and antiphospholipid syndrome with autoimmune thrombocytopenia. Periodontal evolution was followed by monitorization of the periodontal indices: plaque, calculus, bleeding and periodontal pockets indices.
Results. Thrombocytopenia and the cortisone treatment required a complex antibiotic treatment, followed by gingival debridement, after normalization of thrombocytes, by periodontal surgical therapy. 4 weeks after the end of the periodontal treatment, no periodontal pockets were present, any more.
Conclusions. The general condition of the patient plays an important role in the evolution and treatment of the periodontal diseases. Treatment of gingival hyperplasia requires antibiotherapy and, in some cases, even administration of antibiotics.

Keywords:
  • antibiotherapy
  • antiphospholipid syndrome
  • gingival hyperplasia
  • thrombocytopenia