The results of histological investigation on the influence of the proposed drug composition (metronidazole, enterosgel (Sigma), alflutop (Biotehnos S.A., Romania) for experimental mandible bone defect regeneration in rats were presented. The high efficiency and osteoregenerative properties of this paste were shown, and its significant clinical efficiency for temporary placement into the root canals in the treatment of chronic apical periodontitis, for stimulating regeneration of the damaged periapical tissues, was assessed.
Keywords:- alflutop
- enterosgel
- histological investigation
- metronidazole.
- temporary intracanal dressing