The characteristics of our modern society put a lot of pressure on the normal function of the liver and its metabolic role, with an increased intake of fatty and sweet foods, abusive alcohol consumption or over-medication. These elements impact the hepatic function and can favor the onset of conditions such as the non-alcoholic fatty liver disease. This disease can be a gateway towards other metabolic conditions like diabetes mellitus and obesity, since important pathophysiological mechanisms, as insulin resistance, can occur. In periodontal medicine, such metabolic disorders are viewed as high risk factors for the onset of periodontal disease, considering their impact on the host immune response. This lead to the official recognition of periodontal disease as the 6th complication of diabetes mellitus. The studies on the relationship between non-alcoholic fatty liver disease and periodontal disease are scarce and their results are so far inconclusive. However, given the important metabolic processes that the liver controls and their impact on periodontal health and pathology, further studies are required on the matter, in order to clarify the characteristics of this connection.
Keywords:- diabetes mellitus
- insulin resistance
- non-alcoholic fatty liver disease.
- PERIODONTAL DISEASE