CHITOSAN-BASED BIONANOCOMPOSITE FOR TRANSDERMAL THERAPY

Authors: Magdalena AFLOR, Maria SPIRIDON, Maria BUTNARU, Mihaela MÂNDRU, Laura ROMILA, Oana DARABĂ, Alexandra BURLUI

Abstract:

Chitosan has been widely used for tissue engineering of both epithelial and mesenchymal tissues. As major components in various organs, epithelial cells are used in the protection, secretion and maintenance of tissue homeostasis due to their sheet-like tight cellular arrangement and polarised nature. In the regeneration of damaged epithelial tissues, chitosan promotes proliferation of various embryonic and adult epithelial cells. In this study, chitosan-silver- hydroxyapatite (CS/nAg/HAp) hydrogels were prepared by a simple eco-friendly method.

Keywords:
  • biomaterials
  • chitosan
  • hydroxyapatite.
  • silver nanoparticles