EVALUATION OF CLINICOPATHOLOGIC PARAMETERS OF ODONTOGENIC CYSTS IN SOUTH –EAST OF IRAN. A 10 YEAR RETROSPECTIVE STUDY

Authors: Molook TORABI, Maezieh Karimi AFSHAR, Mahsa GHAENIAN, Iman MOHAMMADZADEH

Abstract:

Introduction. The intra-osseous pathologic cysts in jaws comprise a wide range of lesions, from totally benign or locally invasive to frankly malignant ones; each of which mandates a different treatment modality. This study aims at determining the relative frequency of these cysts, as well as their respective clinicopathological findings in patients referred to the two academic centers in Kerman, i.e. Faculty of Dentistry Clinic and Bahonar Medical Complex Hospital, between1997 and 2017. Materials and methods. Based on the available data, this descriptive, analytical and retrospective study was carried out in the archives of the Pathology Departments of Dentistry Faculty and Bahonar Therapeutic Training Hospital (Kerman, South –East Iran), between 1997 and 2017. All medical records with a histological diagnosis of Odontogenic Cysts were included. Demographic data such as gender and age, location of cysts, tentative clinical diagnosis and histopathological findings was collected in a checklist, then analyzed with a SPSS software 21. A P value <0.05 was considered statistically significant. Results and discussion. A total number of 326 patients were included. The lesions were more prevalent in men than women. Radicular cysts were the most prevalent: 54.8% of the total. Dentigerous cysts and odontogenic keratocysts ranked the next most prevalent cases: 17.48 % and 11.34%, respectively. Radicular cysts had the highest concordance rate between the tentative clinical diagnosis versus histopathological findings. Conclusions. This study showed that radicular cysts were the most prevalent subtype of odontogenic cysts. The Kappa coefficient, which measures the inter-rater agreement between the clinical diagnosis and the microscopic diagnosis, was 0.322. Careful clinical examination with appropriate imaging techniques can lead to proper diagnosis of odontogenic cysts.

Keywords:
  • clinical diagnosis
  • histopathologic diagnosis.
  • jaw cysts
  • odontogenic
  • prevalence.