Celiac disease (CD) has become a relatively prevalent disease which associates systemic manifestations mainly conditioned by the dysimmune response triggered by gluten diet. Its oral manifestations have been proven to lead to health disparities and impaired quality of life. Such findings include mainly dental enamel defects (DEDs) and recurrent aphthous stomatitis (RAS). Nevertheless, there are also some potentially severe oral conditions associated with CD, considered to be rare, among which various oral cancers, atrophic glossitis or glossodynia. Thus, the aim of our study was to perform a systematic-review of case presentations reporting rare oral findings associated with CD. The searching protocol was applied to EMBASE, OVID and PubMed. Both pediatric and adult patients were included. The identified conditions include: Plummer-Vinson Syndrome, atrophic glossitis, glossodynia and some oral cancers. Therefore, dental practitioners should be ready to suspect CD also in such rare cases, as prompt management of such conditions could prevent severe and even life threatening complications.Keywords:
- oral cancer.