Introduction: Red clover (RC) is a herbaceous perennial plant growing in temperate and subtropical areas throughout the world. Native Americans traditionally valued RC for the treatment of external skin and lung problems, nervous and reproductive system ailments. The aim of this study was to compare the cytotoxic effect of a commercial mouthwash and red clover based mouthwash.Materials and methods: Red clover plant, purchased in dried form, was crushed and the extract obtained was used to make a mouthwash by adding 50ml of 95% ethanol. Results and discussion: The red clover based mouthwash has a low cytotoxic effect at 5-20 µL. Conclusions: The cytotoxicity assay revealed that the red clover extract can be incorporated in biomedical uses, so that it can be a pioneering step towards the shift to greener medicine.
Keywords:- cytotoxic
- isoflavones
- mouthwash
- red clover