Temporomandibular joint (TMJ) arthritis is a degenerative and inflammatory condition influenced by mechanical loading, oxidative stress, and neuroendocrine factors. Occupational exposure to whole-body vibration (WBV), especially when combined with psychophysical stress, may intensify oxidative imbalance and inflammatory injury in TMJ tissues. Repetitive vibration promotes reactive oxygen species (ROS) generation and cytokine activation, while chronic stress amplifies these effects through sympathetic and cortisol-mediated pathways. Together, these mechanisms accelerate cartilage degradation and synovial inflammation. This review synthesizes current evidence linking WBV exposure and psychophysical stress to TMJ oxidative injury, emphasizing their shared pathogenic pathways. Understanding these associations supports integrative preventive strategies addressing ergonomics, antioxidant protection, and stress management in vibration-exposed and chronically stressed populations.
Keywords:- degenerative joint disorders.
- inflammation
- occupational exposure
- oxidative stress
- psychophysical stress
- REACTIVE OXYGEN SPECIES
- temporomandibular joint arthritis
- whole-body vibration