Soft tissue sarcomas (STS) represent a heterogeneous group of rare malignant tumors, with a wide histopathological spectrum. They affect patient of all ages and often have an unfavourable evolution. Aim of study was to evaluate the incidence of STS, the distribution depending on age, sex, anatomical site of appearance and histological subtypes. Material and method: the study included 67 cases of STS of a total of 922 soft tissue tumors diagnosed and treated during a 12 year period in two major Surgical Clinics in Iaşi. All cases were microscopically examined. For the statistical analysis Microsoft Office Excel and NCSS 2007 (Anova Test) were used. Results: Sarcomas represented 7% of all soft tissue tumors. Distribution depending on age groups shows an increased incidence of STS in children and young adults. Females were slightly more affected than men (52% of cases). The most frequent anatomical site was the lowere extremity (85% of cases), the least common – the retroperitoneal region (3% of cases). Histopathological subtypes were: rhabdomyosarcoma (31% of cases), fibrosarcoma (27%), other subtypes were under 10% (synovial sarcoma, fibrous malignant hystiocytoma) or even under 5% (angiosarcoma, leiomyosarcoma, liposarcoma, MPNST). Rhabdomyosarcoma were mostly seen in patients under the age of 20 (2/3 of cases). Fibrosarcoma, fibrous malignant hystiocytoma, synovial sarcoma, liposarcoma dominated the adult pathology.