Introduction. Early diagnosis of the initial degree of generalized periodontitis (GP) is an effective mode of secondary prevention. This is due to the complexity of understanding the etio-pathogenetic mechanisms of the development generalized parodontal diseases (GPD) and to their high association with a number of diseases of the internal organs and systems with common points of contact between interdependence and mutual influence, particularly with anorexia nervosa (AN). Recently, the incidence of AN has increased significantly, causing serious state, social, psychological and medical problems. The purpose of the present research was to establish the configuration features of generalized periodontal diseases and their clinical manifestations in the form of the basic characteristics of anorexia nervosa. Materials and methods. Clinico-radiological, immunological, analytical and statistical methods were used. 75 patients with AN, aged 18-36 years (average age 26±3.8) – the main group (M) – and 60 patients with GPD without signs of AN of the same age – comparison group (C), which consisted of two subgroups (C1), (C2) with different forms of gingivitis and GP, respectively – were investigated. The control group consisted of 30 subjects similar as to age and sex, without clinical signs of periodontal disease as well as diseases of the internal organs. Results and disscussion. A high incidence of GPD – up to 100% – was diagnosed, including both independent parodontal soft tissue disease and all components of the parodontal complex, characteristic for all age groups and varying with patient age, duration of AN and its stages. Among the independent forms of gingivitis, the most common was chronic catarrhal marginal gingivitis (86.7±8.8%), with some cases of exacerbation against the background of the overwhelming absence of complaints with single manifestations of agrarian, and complex psychological alliance. For all patients with GP, a high degree of tissue sensitization to the bone antigen, characterized by significant changes in the bone component of the parodontal complex with AN, was recorded. GP was predominantly of the I-II degree, with chronic course prevailing over other forms of GPD (80±4.6%). No advantages and priorities of different segments of parodontal complex lesions in patients with AN were observed. Conclusions. A direct correlation and interdependence of generalized parodontal diseases in the form of basic characteristics of AN were established.
Keywords:- anorexia nervosa
- generalized parodontal diseases
- generalized parodontitis
- hypersensibilisation
- marginal catarrhal gingivitis
- osteoporosis